MSc K. Kolovou-Kouri
Bioelectronics (BE), Department of Microelectronics
Expertise: Power-efficient neurostimulation, energy harvesting and ultrasound wireless power transferThemes: Health and Wellbeing
Konstantina Kolovou-Kouri was born in Athens, Greece, in 1992. She received a B.Sc. degree in Electrical Engineering in 2016, specializing in Electronics and Information Technology, followed by an M.Sc. degree in Biomedical Engineering in 2019. Both degrees were acquired from the Technical University of Berlin, Germany. From 2017 to 2019 she worked in the Fraunhofer Institute for Reliability and Microintegration (IZM), in the department of System Integration and Interconnection Technologies.
She joined the Bioelectronics Section at the Delft University of Technology in 2019, where she is currently pursuing her PhD degree. Her research focus lies in the hardware design of versatile neurostimulators, focusing on high efficiency and low power consumption, while also examining the potentials of energy harvesting and wireless power transfer through ultrasound.
- Development of dorsal root ganglion (DRG) multichannel stimulator prototype for use in early clinical trials
K. Kolovou-Kouri; S. Soloukey; B.S. Harhangi; W.A. Serdijn; V. Giagka;
In Book of Abstracts, 8th Dutch Biomedical Engineering Conf. (BME) 2021,
Virtual, 28-29 January 2021.
- Dorsal Root Ganglion (DRG) Versatile Stimulator Prototype Developed for Use in Locomotion Recovery Early Clinical Trials
Konstantina Kolovou-Kouri; Sadaf Soloukey; Frank Huygen en Sanjay Biswadjiet Harhangi; Wouter Serdijn; Vasiliki Giagka;
In Proc. 2021 10th International IEEE/EMBS Conference on Neural Engineering (NER),
Online, IEEE, May 4-6 2021.
Keywords: ...Neural Interfaces - Neural stimulation, Motor Neuroprostheses - Neuromuscular stimulation, Neuromuscular Systems - Locomotion, posture and balance.
Abstract: ...This paper presents the development of a Dorsal Root Ganglion (DRG) stimulator system intended for use in early clinical trials for motor recovery after Spinal Cord Injury (SCI). It allows for independent control of multisite/multilevel bilateral (on both sides of the spinal cord) stimulation, it can supply a high output current of 25.4mA, and has the ability to program pulse sequences similar to actual locomotion patterns. These characteristics ultimately provide the required versatility for examining the effects of DRG stimulation on locomotion recovery, which is lacking in currently available commercial systems. The device is created using commercially available components to make the design reproducible by other research labs and to facilitate the critical approval procedure for use in a clinical research environment. Throughout the design phase, essential considerations regarding the safety of the participating patient, as well as of the medical personnel involved, were taken into account and these are analyzed and demonstrated in this paper. Such considerations are very rarely discussed in scientific literature and the authors consider that, apart from the design of the system itself, this discussion is a critical contribution of this paper.
Last updated: 3 Jun 2020