MSc Paul Motreuil-Ragot

PhD student
Electronic Components, Technology and Materials (ECTM), Department of Microelectronics

Themes: Health and Wellbeing


My research interest is focused on microfabrication and material science for Organs-on-chip (OoCs). My doctoral work concerns the development of a smart material-based OoC platform that could allow actuation and sensing of tissue activity using the same culture substrate, as well as on-chip microfluidic pumping.

I got my master's degree in Biomedical Engineering from Université de Strasbourg, France. During my studies, I had the opportunity to do several internships in both public and private institutes. In particular, I had a 4-month experience in TissUse Gmbh (Berlin, Germany) where I developed a computer vision software for automation of measurements in OoCs. I did my master thesis in the French Alternative Energies and Atomic Energy Commission (CEA, Grenoble), where I could develop a 3D skin-on-chip model using hydrogel and Micronit’s OoC platform. During my past experiences I could learn a lot about tissue engineering, microfluidic and innovation.
Now I have the privilege to collaborate with multi-disciplinary teams within the Netherlands Organ-on-Chip Initiative (NOCI) and to perform collaborations to manufacture innovative silicon/polymer-based OoC devices.

Netherlands Organ-on-Chip Initiative

To develop new microphysiological platforms to better predict the effect of medicines, based on a combination of human stem cells and microtechnology.

  1. Microelectronmechanical organs-on-chip
    Massimo Mastrangeli; Hande Aydogmus; Milica Dostanic; Paul Motreuil-Ragot; Nele Revyn; Bjorn de Wagenaar; Ronald Dekker; Pasqualina M. Sarro;
    In 21st Int. Conf. on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS 2021),
    online, 20-25 June, 2021.

  2. Enabling Actuation and Sensing in Organs-On-Chip Using Electroactive Polymers
    P. Motreuil-Ragot; A. Hunt; D. Kasi; B. Brajon; A. M. J. M. van den Maagdenberg; V. Orlova; M. Mastrangeli; P. M. Sarro;
    In IEEE 3rd International Conference on Soft Robotics (RoboSoft 2020),
    2020. DOI: 10.1109/RoboSoft48309.2020.9115977

  3. Enabling actuation and sensing in organs-on-chip using electroactive polymers
    P. Motreuil-Ragot; A. Hunt; D. Kasi; B. Brajon; A. van den Maagdenberg; V. Orlova; M. Mastrangeli; P. M. Sarro;
    In International MicroNanoConference,
    Utrecht (NL), December 10-11, 2019.

  4. Microengineered organs-on-chip
    H. Aydogmus; M. Dostanic; P. Motreuil-Ragot; M. Mastrangeli; P. M. Sarro;
    Poster, presented at QBio Symposium, Utrecht (NL), October 29, 2019.

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Last updated: 6 Oct 2020