dr.ir. M.N. van Dongen

PhD student
Bioelectronics (BE), Department of Microelectronics

PhD thesis (Apr 2015): Design of efficient and safe neural stimulators: A multidisciplinary approach
Promotor: Wouter Serdijn, Paddy French

Expertise: Electrophysiology and Circuit Design of Neural Stimulators. Focus on novel stimulation strategies to increase power efficiency of neural stimulation.

Themes: Health and Wellbeing

Biography

Marijn van Dongen was born in Pijnacker, The Netherlands in 1984. He received the MSc and BSc (cum laude) degrees in Electrical Engineering from the Delft University of Technology in 2007 and 2010, respectively.

He is currently working towards his PhD in the Section Bioelectronics at the Microelectronics department of Delft University of Technology. His research interests include the design of neural stimulator output circuits as well as the modeling of the electrophysiological and electrochemical processes during electrical stimulation.

He has served as the Financial Chair of the IEEE BioCAS2013 conference.

Projects history

SINs - Smart Implantable Neurostimulators

In this research program we push the research and development of technology for research on and treatment of a multitude of brain disorders, a.o., tinnitus and addiction.

  1. An Ultra High-Frequency 8-Channel Neurostimulator Circuit with 68% Peak Power Efficiency
    Alessandro Urso; Vasiliki Giagka; Marijn Van Dongen; Wouter A. Serdijn;
    IEEE Transactions on Biomedical Circuits and Systems,
    2019. DOI: 10.1109/TBCAS.2019.2920294
    document

  2. AN ULTRA HIGH-FREQUENCY 8-CHANNEL NEUROSTIMULATOR CIRCUIT WITH 68% PEAK POWER EFFICIENCY
    A. Urso; M. van Dongen; W.A. Serdijn;
    In Book of Abstracts, 7th Dutch Biomedical Engineering Conf. (BME) 2019,
    Jan. 24-25 2019.
    document

  3. An Ultra High-Frequency 8-Channel Neurostimulator Circuit with 68% Peak Power Efficiency
    Alessandro Urso; Vasiliki Giagka; Marijn Van Dongen; Wouter A. Serdijn;
    In Book of Abstracts, 2019 International Symposium on Integrated Circuits and Systems (ISICAS 2019),
    Venice, Italy, IEEE, 29-30 August 2019. DOI: 10.1109/TBCAS.2019.2920294
    document

  4. An Ultra High-Frequency Multi-Channel Neurostimulator Circuit with Unprecedented Power Efficiency
    Alessandro Urso; Marijn Van Dongen; Wouter Serdijn;
    In Book of Abstracts, 6th Dutch Bio-Medical Engineering Conference, 26 and 27 January 2017, Egmond aan Zee, The Netherlands,
    2017.
    document

  5. A Broadband Polyvinylidene Difluoride-Based Hydrophone with Integrated Readout Circuit for Intravascular Photoacoustic Imaging
    V. Daeichin; C. Chen; Q. Ding; M. Wu; R. Beurskens; G. Springeling; E. Noothout; M. D. Verweij; K. W. A. van Dongen; J. G. Bosch; A. F. W van der Steen; N. de Jong; M. Pertijs; G. van Soest;
    Ultrasound in Medicine \& Biology,
    Volume 42, Issue 5, pp. 1239‒1243, May 2016. DOI: 10.1016/j.ultrasmedbio.2015.12.016
    Abstract: ... Intravascular photoacoustic (IVPA) imaging can visualize the coronary atherosclerotic plaque composition on the basis of the optical absorption contrast. Most of the photoacoustic (PA) energy of human coronary plaque lipids was found to lie in the frequency band between 2 and 15 MHz requiring a very broadband transducer, especially if a combination with intravascular ultrasound is desired. We have developed a broadband polyvinylidene difluoride (PVDF) transducer (0.6 × 0.6 mm, 52 μm thick) with integrated electronics to match the low capacitance of such a small polyvinylidene difluoride element (<5 pF/mm2) with the high capacitive load of the long cable (∼100 pF/m). The new readout circuit provides an output voltage with a sensitivity of about 3.8 μV/Pa at 2.25 MHz. Its response is flat within 10 dB in the range 2 to 15 MHz. The root mean square (rms) output noise level is 259 μV over the entire bandwidth (1–20 MHz), resulting in a minimum detectable pressure of 30 Pa at 2.25 MHz.

  6. Design of Efficient and Safe Neural Stimulators - a multidisciplinary approach
    Marijn van Dongen; Wouter Serdijn;
    Springer, in Analog Circuits and Signal Processing, 2016. DOI: 10.1007/978-3-319-28131-5.
    document

  7. Balancing Accuracy, Delay and Battery Autonomy for Pervasive Seizure Detection
    Athanasios Karapatis; Robert Mark Seepers; Marijn van Dongen; Wouter A. Serdijn; Christos Strydis;
    In 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2016),
    Orlando, Florida, USA, IEEE, August 16-20 2016.
    document

  8. A broadband PVDF-based hydrophone with integrated readout circuit for intravascular photoacoustic imaging
    V. Daeichin; C. Chen; Q. Ding; M. Wu; R. Beurskens; G. Springeling; E. Noothout; M. D. Verweij; K. W.A. van Dongen; J. G. Bosch; A. F. W van der Steen; N. de Jong; M. Pertijs; G. van Soest;
    In Proc. SPIE Photonics West,
    SPIE, February 2016. DOI: 10.1016/j.ultrasmedbio.2015.12.016
    Abstract: ... Intravascular photoacoustic (IVPA) imaging can visualize the coronary atherosclerotic plaque composition on the basis of the optical absorption contrast. Most of the photoacoustic (PA) energy of human coronary plaque lipids was found to lie in the frequency band between 2 and 15 MHz requiring a very broadband transducer, especially if a combination with intravascular ultrasound is desired. We have developed a broadband polyvinylidene difluoride (PVDF) transducer (0.6 × 0.6 mm, 52 μm thick) with integrated electronics to match the low capacitance of such a small polyvinylidene difluoride element (<5 pF/mm2) with the high capacitive load of the long cable (∼100 pF/m). The new readout circuit provides an output voltage with a sensitivity of about 3.8 μV/Pa at 2.25 MHz. Its response is flat within 10 dB in the range 2 to 15 MHz. The root mean square (rms) output noise level is 259 μV over the entire bandwidth (1–20 MHz), resulting in a minimum detectable pressure of 30 Pa at 2.25 MHz.

  9. A 0.042 mm^2 programmable biphasic stimulator for cochlear implants suitable for a large number of channels
    W. Ngamkham; M.N. van Dongen; W.A. Serdijn; C.J. Bes; J.J. Briaire; J.H.M. Frijns;
    ArXiv.org,
    January 29 2015.
    document

  10. Cerebellar output controls generalized spike-and-wave discharge occurrence
    Kros, Lieke; Eelkman Rooda, Oscar H.J.; Spanke, Jochen K.; Alva, Parimala; van Dongen, Marijn N.; Karapatis, Athanasios; Tolner, Else A.; Strydis, Christos; Davey, Neil; Winkelman, Beerend H.J.; Negrello, Mario; Serdijn, W;
    Annals of Neurology,
    Volume 77, Issue 6, pp. 1027-1049, June 2015.
    document

  11. High frequency switched-mode stimulation can evoke postsynaptic responses in cerebellar principal neurons
    Dongen, Marijn van; Hoebeek, Freek; Koekkoek, S K E; De Zeeuw, Chris; Serdijn, Wouter;
    Frontiers in Neuroengineering,
    Volume 8, Issue 2, 2015.
    document

  12. Does a coupling capacitor enhance the charge balance during neural stimulation? An empirical study
    van Dongen, Marijn N.; Serdijn, Wouter A.;
    Medical & Biological Engineering & Computing,
    pp. 1-9, May 29 2015.
    document

  13. A Power-Efficient Multichannel Neural Stimulator Using High-Frequency Pulsed Excitation
    Marijn N. van Dongen; Wouter A. Serdijn;
    In Book of Abstracts, 5th Dutch Bio-Medical Engineering Conference,
    Egmond aan Zee, the Netherlands, January 22-23 2015.
    document

  14. Design of efficient and safe neural stimulators: a multidisciplinary approach
    Marijn N. van Dongen;
    PhD thesis, Delft University of Technology, Section Bioelectronics, April, 24 2015.
    document

  15. Efficacy of high frequency switched-mode stimulation in activating purkinje cells
    M. van Dongen; F. Hoebeek; S. Koekkoek; C. de Zeeuw; W. Serdijn;
    ArXiv.org,
    June 2014.
    document

  16. A Power-Efficient Multichannel Neural Stimulator Using High-Frequency Pulsed Excitation From an Unfiltered Dynamic Supply
    Marijn van Dongen; Wouter A. Serdijn;
    IEEE Transactions on Biomedical Circuits and Systems,
    2014. Digital Object Identifier: 10.1109/TBCAS.2014.2363736.
    document

  17. Absence Seizures Stopped by Closed-Loop Activation of Cerebellar Output
    Lieke Kros, Oscar H.J. Eelkman Rooda, Jochen Spanke, Parimala Alva; Marijn N. van Dongen; Thanasis Karapatis, Else A. Tolner; Christos Strydis, Neil Davey, Beerend H. Winkelman, Mario Negrello; Wouter A. Serdijn, Volker Steuber, Arn M.J.M. van;
    In Federation of European Neuroscience Societies (FENS) Forum of Neuroscience 2014,
    Milan, Italy, July 5-9 2014.

  18. Li-Ion charger circuit for implantable pulse generator
    R.C. van Dongen; S. Hiseni; W.A. Serdijn;
    In Book of Abstracts, 4th Dutch Conference on Bio-Medical Engineering (BME),
    Egmond aan Zee, the Netherlands, Jan. 24-25 2013.

  19. A charge balanced biphasic stimulator circuit for cochlear implants
    Wannaya Ngamkham; Marijn van Dongen; Wouter Serdijn;
    In Book of Abstracts, 4th Dutch Conference on Bio-Medical Engineering (BME),
    Egmond aan Zee, the Netherlands, Jan. 24-25 2013.

  20. A power efficient and reliable neurostimulator system operating at very high frequency
    Marijn van Dongen; Wouter Serdijn;
    In Book of Abstracts, 4th Dutch Conference on Bio-Medical Engineering (BME),
    Egmond aan Zee, the Netherlands, Jan. 24-25 2013. This presentation (by Marijn) received the best presentation award at the conference.

  21. A Switched-Mode Multichannel Neural Stimulator with a Minimum Number of External Components
    Marijn van Dongen; Wouter A. Serdijn;
    In Proc. International Symposium on Circuits and Systems (ISCAS),
    Beijing, China, IEEE, May 19-23 2013.
    document

  22. A transistor-only power-efficient high-frequency voltage-mode stimulator for a multichannel system
    Marijn N. van Dongen; Wouter A. Serdijn;
    In Proc. Biomedical Circuits and Systems Conference (BioCAS 2013),
    Rotterdam, the Netherlands, IEEE, pp. 93-96, Oct. 31 - Nov. 2013.
    document

  23. Tissue- or neurostimulator
    Marijn van Dongen; Wouter Serdijn; Dirk de Ridder;
    Patent, Dutch NL2008217C, Aug 2013. Assignee: Univ Delft Tech.
    document

  24. Does enriched acoustic environment in humans abolish chronic tinnitus clinically and electrophysiologically? A double blind placebo controlled study
    Vanneste, S; van Dongen, M; De Vree, B; Hiseni, S; van der Velden, E; Strydis, C; Kathleen, J; Norena, A; Serdijn, W; De Ridder, D;
    Hearing Research,
    Oct. 23 2012. pii: S0378-5955(12)00244-4. doi: 10.1016/j.heares.2012.10.003.
    document

  25. Biphasic Stimulator Circuit for a Wide Range of Electrode-Tissue Impedance Dedicated to Cochlear Implants
    Wannaya Ngamkham; Marijn N. van Dongen; Wouter A. Serdijn;
    In Proc. International Symposium on Circuits and Systems (ISCAS),
    Seoul, South Korea, IEEE, pp. 1083-1086, May 20-23 2012.
    document

  26. An Implementation of Least-Voltage Drop Stimulator Circuit for Cochlear Implants
    Wannaya Ngamkham; Marijn van Dongen; Wouter A. Serdijn;
    In Book of Abstracts, ICT.Open,
    Rotterdam, the Netherlands, Oct. 22-23 2012.
    document

  27. A 10MHz Switched-mode power efficient neural stimulator
    Marijn van Dongen; Wouter A. Serdijn;
    In Book of Abstracts, 4th International Conference on Neuroprosthetic Devices (ICNPD-2012),
    Freiburg, Germany, Nov. 19-20 2012.
    document

  28. Design and prototype development of a wearable neural stimulator system with flexible waveform adjustments
    Marijn van Dongen; Wouter Serdijn; Robert van Spyk; Christos Strydis; Georgi Gaydadjiev;
    In Book of Abstracts, 3rd Dutch Conference on Bio-Medical Engineering (BME),
    Egmond aan Zee, the Netherlands, Jan. 20-21 2011.

  29. A 0.5V Signal-Specific Continuous-Time Level-Crossing ADC with Charge Sharing
    Yongjia Li; Marijn van Dongen; Wouter A. Serdijn;
    In Proc. Biomedical Circuits and Systems Conference (BioCAS),
    San Diego, CA, USA, IEEE, Nov. 10-12 2011.
    document

  30. Design of a versatile voltage based output stage for implantable neural stimulators
    Marijn N. van Dongen; Wouter A. Serdijn;
    In Proc. Latin-American Symposium on Circuits and Systems (LASCAS),
    Iguasu Falls, Brazil, IEEE, Feb. 24-26 2010.
    document

  31. A Least-Voltage Drop High Output Resistance Current Source for Neural Stimulation
    Chutham Sawigun; Wannaya Ngamkham; Marijn van Dongen; Wouter A. Serdijn;
    In Proc. Biomedical Circuits and Systems Symposium (BioCAS),
    Paphos, Cyprus, IEEE, Nov. 3-5 2010.
    document

  32. Design of a Low Power 100 dB Dynamic Range Integrator for an Implantable Neural Stimulator
    Marijn van Dongen; Wouter A. Serdijn;
    In Proc. Biomedical Circuits and Systems Symposium (BioCAS),
    Paphos, Cyprus, IEEE, Nov. 3-5 2010.
    document

  33. Design of a general purpose implantable brain tissue stimulator
    Marijn N. van Dongen; Wouter A. Serdijn;
    In Book of Abstracts, Dutch Conference on Biomedical Engineering (BME),
    Egmond aan Zee, the Netherlands, Jan. 22-23 2009.

BibTeX support

Last updated: 26 Dec 2018

Marijn van Dongen

Alumnus
  • Left in 2015
  • Now: NXP, Nijmegen, the Netherlands

MSc students