REASONS – Realtime Sensing of Neural Signals (REASONS)

Themes: Health and Wellbeing

This project targets the development of a completely new readout system for measuring the so called electrically evoked compound action potential (eCAP) coming from the auditory nerve.
Dutch Technology Foundation (STW) project (11693) "REASONS – Realtime Sensing of Neural Signals" (2011 – ), project leader: dr. W.A. Serdijn. This project targets the development of a completely new readout system for measuring the so called electrically evoked compound action potential (eCAP) coming from the auditory nerve. To develop this readout system, new electronic circuitry will be designed based on state of the art technologies integrated with the electrode itself. Existing systems will be tested extensively to develop novel measurement algorithms for the new readout system. Animal experiments will be performed on existing and new readout systems. We expect to come up with circuits and systems for reading out neural responses that offer more functionality, better performance and enjoy a drastically reduced form factor and power consumption. Clinically, the neural response will give new insight in the potential of eCAP recordings and take the first step in moving toward fitting to the patient without subjective data. Future patients will be rehabilitated better and faster with the newly developed methods.

Project data

Researchers: Wouter Serdijn, Cees-Jeroen Bes, Yongjia Li
Starting date: September 2011
Closing date: September 2016
Sponsor: STW
Partners: Leiden University Medical Center (LUMC), ENT department (prof. Johan Frijns, dr. Jeroen Briaire)
Users: Advanced Bionics, Synaptix, SystematIC, the Brain Research center for Advanced, Innovative and Interdisciplinary Neuromodulation
Contact: Wouter Serdijn

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